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Updated: Jan 7, 2026

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
08:15

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

Published on: October 6, 2014

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对CHEK2相关癌症倾向的基因组检测

Sun Young Kim1,2, Jung Kim1, Mark Ramos1,3

  • 1Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland.

JAMA network open
|December 15, 2025
PubMed
概括

患有CHEK2致病变体的个人有几种癌症的风险增加,包括乳腺癌和前列腺癌. 这项研究量化了大型队列中的患病率和癌症风险,发现了较低的过度死亡率和癌症风险 (odds比率<2).

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