结合认知处理疗法与恒星性关节阻断的有效性:一个开放式随机等待列表临床试验
Psychotherapy and psychosomatics
|December 15, 2025
概括
星状质块 (SGB) 增强了军事人员和退伍军人患有创伤后应激障碍 (PTSD) 的认知处理疗法 (CPT). 在CPT之前接受SGB提供更快的症状减轻,而CPT后的SGB有利于非响应者.
科学领域:
- 精神病学和行为健康
- 创伤和与压力有关的疾病.
- 麻醉学 麻醉学
背景情况:
- 创伤后应激障碍 (PTSD) 对军事人员和退伍军人产生重大影响.
- 认知处理疗法 (CPT) 是一线治疗,但有些患者需要额外的干预措施.
- 星状质块 (SGB) 通过调节同情性兴奋来减少PTSD症状.
研究的目的:
- 研究SGB的有效性,作为对PT后应激障碍群体性CPT的辅助治疗.
- 为了比较SGB管理的时间 (在CPT之前与之后) 对治疗结果.
主要方法:
- 一个开放的,随机的等待列表试验,涉及86名军事人员和退伍军人.
- 参与者在一次大规模CPT课程之前或之后接受了SGB.
- 使用DSM-5 (PCL-5) 的PTSD检查清单来评估PTSD症状.
主要成果:
- 在SGB-before-CPT和SGB-after-CPT组中,PCL-5得分与基线相比显著降低.
- 在SGB-before-CPT组经历了更快的症状减轻.
- 在SGB-after-CPT组的参与者在第8周没有达到缓解,在第12周接受SGB后显著改善.
结论:
- SGB增强了军事人口中PTSD的CPT的有效性.
- 在CPT之前给药SGB可能会加速治疗反应.
- 对于那些对CPT初始疗程没有充分反应的人来说,SGB是一种可行的选择.
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