耳植入后的动态功能连接:预测语音结果和探索大脑网络动态.
Jamal Esmaelpoor1,2, Tommy Peng1,2, Beth Jelfs3
1Department of Medical Bionics, University of Melbourne, Parkville, VIC 3052, Australia.
概括
耳植入器 (CI) 后的大脑网络动态预测听力结果. 植入后早期较低的大脑网络切换率和特定的交叉模式可塑性与更好的语音理解相关,有助于个性化康复.
科学领域:
- 神经科学是一个神经科学.
- 听觉神经科学 听觉神经科学
- 神经成像是一种神经成像.
背景情况:
- 耳植入物 (CIs) 提供听力恢复,但结果各不相同.
- 预测CI的成功和理解大脑可塑性仍然是一个挑战.
研究的目的:
- 为了研究CI植入后大脑功能网络的时间动态.
- 为了确定语音理解结果的预测因素,并探索大脑的可塑性.
主要方法:
- 功能近红外谱学 (fNIRS) 测量了29名CI候选人和23名对照者的大脑活动.
- 使用多层模块化和网络切换速率分析大脑社区动态.
- 1年后评估语音理解,植入后1个月和1年的fNIRS.
主要成果:
- 在CI后1个月的较低网络切换率与更好的1年语音表现有关.
- 早期观察到后 (PT) 与视觉皮层连接性 (跨模态可塑性) 的增加,减少1年.
- 随着时间的推移,CI用户的半球间PT连接得到了改善,减少了与对照者的差异.
结论:
- 动态功能连接模式是CI结果变化的有意义的神经相关物.
- 早期的网络动态和跨模式可塑性可能预测长期的语音理解.
- 研究结果支持个性化康复策略,以优化CI结果.
相关概念视频
01:31Hearing
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
01:22Hair Cells
Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
01:13The Cochlea
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
01:10Higher Mental Functions of the Brain: Language
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
01:15Auditory Pathway
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...