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欧亚十字路口的炎症性肠病趋势:多中心数据十年
Filiz Akyüz1, Besim Fazil Ağargün1, Özlen Atuğ2
1Division of Gastroenterohepatology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University.
在土耳其,炎症性肠病 (IBD) 的诊断量翻了一番,而性结肠炎 (UC) 现在比克罗恩病 (CD) 更常见. 存在区域差异,强调需要国家登记册和有针对性的医疗保健资源.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,炎症性肠病 (IBD) 的发病率正在增加,特别是在新兴工业化国家.
- 在土耳其,关于IBD的国家代表性流行病学数据很少.
- 本研究旨在描述土耳其IBD诊断的最新趋势.
研究的目的:
- 从2010年到2022年,分析土耳其新诊断的IBD的流行病学趋势.
- 描述IBD患者的临床特征和地理分布.
- 确定与特定IBD诊断相关的因素.
主要方法:
- 一项回顾性多中心队列研究,涉及3463名在土耳其24个中心新诊断的IBD成年患者.
- 收集的数据包括人口统计,疾病行为,吸烟状况,家族史和地理居住地.
- 使用统计方法分析时间和区域模式,包括千二测试和细分回归.
主要成果:
- 2010年至2021年,每年IBD诊断的数量增加了一倍以上.
- 性结肠炎 (UC) 诊断超过了克罗恩病 (CD) 诊断,UC-CD比率显著增加.
- 观察到IBD患病率的西向东梯度,马尔马拉和爱琴海地区的负担更高. 在CD患者中,吸烟和家族病史更为普遍.
结论:
- 在土耳其,IBD的发病率呈现稳步增长,UC现在比CD更为普遍.
- 患者通常在成年早期被诊断出来.
- 由于区域和医院一级的显著差异,需要建立国家IBD注册表和战略资源配置.
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