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实时剂量测量,器官剂量和风险评估,用于IGRT程序中的CBCT胸部协议

A Campos¹, A C Sá², Y Romanets³

¹Radiotherapy Physics Department of Dra.Natália Chaves Cancer Center-Joaquim Chaves Saúde, Rua Anibal, Bettencourt, 3, 2790-225, Carnaxide, Portugal.

Radiography (London, England : 1995)

|December 15, 2025

概括

在放射治疗中,每日圆束计算机断层扫描 (CBCT) 会增加患者的辐射暴露. 这项研究使用幻影估计了器官剂量和癌症风险,发现肺部的风险最高. 准确的器官剂量评估对于更好的CBCT协议至关重要.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学
放射性成像学成像学

背景情况:

圆束计算机断层扫描 (CBCT) 对于图像导向放射治疗 (IGRT) 是至关重要的,它提高了治疗的准确性,但增加了患者的辐射暴露.
常规CBCT可以导致大量的累积辐射剂量,尽管使用剂量减少技术,但需要仔细评估.

研究的目的:

使用MOSFET探测器估计胸部CBCT期间放射敏感器官 (肺,胃,肝) 吸收的辐射剂量.
用物理胸部幻影和BEIR VII模型计算成年人癌症发病率和死亡率的相关风险.

主要方法:

使用金属氧化物半导体场效应晶体管 (MOSFET) 探测器来测量成人胸腔幻体内特定器官吸收的剂量.
根据估计的器官剂量,使用BEIR VII模型分析癌症发病率和死亡风险.
将MOSFET的剂量评估与其他方法比较,例如蒙特卡洛模拟和热发光剂量计 (TLD).

主要成果:

吸收剂量在异中中心附近的器官中从每小部分3-8mGy不等,在33个小部分中达到大约260mGy.
根据BEIR VII模型,在20至80岁的年龄段,肺癌发病率风险最高.
肺部剂量估计从2.08mGy到7.60mGy不等,而心脏剂量在不同的评估方法中从4.9 Gy到10 mGy不等.

结论:

直接的器官吸收剂量评估是优先考虑的替代方法,以准确评估接受CBCT的患者的辐射风险.
协调实验剂量计幻影研究可以提高器官剂量评估的准确性.
改善剂量评估和风险沟通对于在临床实践中关于最佳CBCT协议的知情决策至关重要.

关键词:

吸收的剂量吸收的剂量癌症发病率风险癌症发生率风险圆束CT CT 圆束低剂量的低剂量在 MOSFET 探测器中,

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