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Updated: Jun 7, 2026

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单细胞蛋白质组分析在人类质母细胞瘤中定义了离散的中性粒细胞功能状态

Pranvera Sadiku1, Alejandro J Brenes2, Rupert L Mayer3,4,5

  • 1Center for Inflammation Research, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK.

Nature communications
|December 15, 2025
PubMed
概括

这项研究使用先进的蛋白质组学揭示了质母细胞瘤瘤中明显的中性粒细胞状态. 这些发现通过发现致病性和抗瘤性中性粒细胞子集来确定潜在的治疗点.

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相关概念视频

Mitochondrial Membranes01:45

Mitochondrial Membranes

A single mitochondrion is a bean-shaped organelle enclosed by a double-membrane system. The outer membrane of mitochondria is smooth and contains many porins - the integral membrane transporters. Porins enable free diffusion of ions and small uncharged molecules through the outer mitochondrial membrane but limit the transport of molecules larger than 5000 Daltons. Further, the outer mitochondrial membrane forms a unique structure called membrane contact sites with other subcellular organelles,...