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Updated: Jun 21, 2026

Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy
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编码Sm-TSP-2变异形式的mRNA疫苗赋予了对Schistosoma mansoni的保护性免疫力

Athos Silva de Oliveira1,2, Sevan Alwan3, Philip T LoVerde4

  • 1Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, USA.

NPJ vaccines
|December 15, 2025
PubMed
概括

新的mRNA疫苗以向Schistosoma mansoni tetraspanin-2 (Sm-TSP-2) 为目标,显示出有希望的结果. 膜固的Sm-TSP-2细胞外循环 (EC2) mRNA疫苗显著降低了小鼠中的寄生虫负担.

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