多个队列的证据表明,在老年人中,牙症与虚弱有关
1Department of Dentistry, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, China. jun_he@zju.edu.cn.
Scientific reports
|December 15, 2025
概括
完全失去牙 (牙) 与中国,英国和美国老年人的脆弱性增加有关. 这凸显了口腔健康在评估和管理老年人口脆弱性的重要性.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 牙科医学 牙科医学
背景情况:
- 虚弱是一种严重的老年综合征,与不良健康结果有关.
- 牙病,或完全失去牙,是全世界老年人口中普遍存在的疾病.
- 牙病和脆弱性之间的关系需要在不同的人口群体中进行进一步的调查.
研究的目的:
- 为了检查结牙症和脆弱性之间的关联.
- 在中国,英国和美国的全国代表队伍中分析这一关联.
- 通过元分析综合发现,得出可靠的结论.
主要方法:
- 统一分析了来自中国健康与退休调查 (CHARLS),英国老龄化纵向研究 (ELSA) 和健康与退休研究 (HRS) 的纵向数据.
- 多变量回归模型根据年龄,性别,生活方式和并发症进行调整.
- 固定和随机效应的元分析,以跨队列的效应估计进行聚合.
主要成果:
- 与有牙的人相比,有牙的人的脆弱指数得分显著更高 (整体平均差异=2.68),脆弱的几率增加 (整体几率比=1.38),与有牙的人相比.
- 在按年龄和性别分层分析以及解决缺失数据后,关联仍然显著和强大.
- 在三个队列中,共有27,274名参与者被纳入.
结论:
- 埃登图主义独立地与老龄化人口的脆弱性增加有关.
- 口腔健康状况是老年风险评估的一个重要因素.
- 这些发现支持将牙科评估纳入多学科脆弱性管理策略.
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