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Updated: Jan 8, 2026

Purification of Ubiquitinated p53 Proteins from Mammalian Cells
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SLAP通过UBE3C介导的非降解的mLST8ubiquitination来控制mTORC2的完整性,以抑制结直肠瘤发生

Rudy Mevizou1,2, Dana Naim1,2,3, Florent Cauchois1,3

  • 1CRBM, Université de Montpellier, CNRS, Montpellier, France.

Cell death and differentiation
|December 15, 2025
PubMed
概括

类似Src的适配蛋白 (SLAP) 通过调节mTORC2的完整性来抑制结直肠癌 (CRC). SLAP针对mLST8进行无处不在,抑制癌细胞生长和入侵,为CRC提供新的治疗策略.

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