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Updated: Jun 12, 2026

Multiplexed Single-molecule Force Proteolysis Measurements Using Magnetic Tweezers
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用于分析强力激活蛋白质扩展和相互作用的DNA纳米设备

Kun Zhou1,2, Minhwan Chung1,3, Shankar Pandey1,3

  • 1Department of Cell Biology, Yale School of Medicine, New Haven, USA, CT.

Nature nanotechnology
|December 15, 2025
PubMed
概括

研究人员开发了一种DNA纳米装置,可以对蛋白质施加受控的力量,从而使得机械敏感蛋白如塔林1的生物化学研究成为可能,并确定了新的结合伙伴.

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相关概念视频

Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...