新诊断的乳病儿童的体重指数:系统性审查和元分析
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Updated: Jan 8, 2026

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Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
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Farzad Maleki1, Marjan Hosseinpour2,3, Mohammad Reza Pashaei2,4
1Student Research Committee, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
European journal of pediatrics
|December 16, 2025
概括
儿童的乳病 (CeD) 越来越多地被诊断为正常体重和超重的个体,而不仅仅是体重不足的人. 这项研究强调了在儿童中考虑CeD的必要性,无论BMI如何,以获得更早的诊断和更好的结果.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 儿童的乳病 (CeD) 呈现正在演变,超越了与体重不足的传统关联.
- 最近的证据表明,正常体重和超重/肥胖儿童的CeD患病率正在上升,这挑战了以前的诊断假设.
研究的目的:
- 确定在开始无质饮食 (GFD) 之前被诊断患有CeD的儿童的体重指数 (BMI) 状态.
- 分析儿童CeD患者在诊断时体重不足,正常体重和超重/肥胖的全球患病率.
主要方法:
- 一项对32项涉及14169名患有CeD儿童的观察性研究的系统综述和元分析.
- 搜索了PubMed,Scopus和Web of Science数据库,遵守了PRISMA和MOOSE的指导方针.
- 使用I2统计评估异质性,使用漏斗图和埃格尔测试评估出版偏差,使用纽卡斯尔-太华尺度评估偏差风险.
主要成果:
- 体重不足的综合流行率为15.3%,而超重/肥胖在诊断时为10.5%.
- 与高收入国家 (9.6%) 相比,低收入和中等收入国家 (35.5%) 的低体重患病率明显高于高收入国家 (9.6%).
- 低体重最多的地区是地中海东部地区 (31.9%),超重/肥胖最多的地区是西太平洋地区 (21.4%) 和欧洲地区 (12.0%).
结论:
- 在诊断时患有CeD的儿童中,正常体重和超重/肥胖的患病率高于以前的预期,特别是在高收入国家.
- 这项研究强调了诊断儿童出现暗示性症状的CeD的重要性,无论他们的BMI如何.
- 所有BMI类别的早期诊断可以改善长期的临床结果和患者的生活质量.
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