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Updated: Jan 8, 2026

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging

Published on: October 16, 2017

安全的光学反自动激光光:在临床系统中实现组织传感器.

Nadezhda Korneva^1,2, Gleb Budylin³, Polina Tseregorodtseva¹

¹Faculty of Physics, Lomonosov Moscow State University, Moscow, Russia.

Lasers in surgery and medicine

|December 16, 2025

概括

这项研究引入了激光石术的光学反系统,可以区分尿 पथ与软组织. 该系统通过最大限度地减少对非目标组织的无意激光暴露来提高程序安全性.

关键词:

扩散反射光谱学扩散反射光谱学激光石化三维精神治疗实时组织分化实时组织分化.

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科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
光学工程是指光学工程.
医疗器械医疗器械

背景情况:

激光石术是清除尿路结石的常见手术.
周围软组织的意外损伤是激光石术期间的潜在风险.
目前的方法缺乏实时区分石头和组织.

研究的目的:

开发一个光学反系统,以实时区分尿路结石和软组织.
为了提高激光石术手术的安全性和精度.
将该系统与商业手术激光器集成.

主要方法:

分散反射光谱法 (DRS) 在临床疗神平台上使用.
在体内实验中,收集和分析了激光石术期间组织的DRS光谱.
机器学习算法,包括主要组件分析 (PCA) 和线性差异分析 (LDA),用于分类.

主要成果:

该系统在软组织识别方面获得了93%的灵敏度,在使用LDA检测石头方面获得了93%的特异性.
实时差异化有效地减少了对非目标组织的无意激光暴露.
在区分石头和软组织方面,证明了高的诊断性能.

结论:

开发的光学引导系统在激光石化术期间提供实时反.
它通过减少意外组织损伤的风险,显著提高了程序安全性.
预计这项技术将提高微创性泌尿器官激光手术的结果.