饮食中的能量水平通过调节乳头微生物群来调节乳头代谢物和羊的功能
Yize Song1, Senxuan Hou1, Yuping Xiang1
1State Key Laboratory of Animal Biotech Breeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
BMC microbiology
|December 16, 2025
概括
高能量的饮食会改变羊的肠微生物和新陈代谢. 养高能量的饮食改变了主导细菌的平衡,促进了碳水化合物代谢,并改变了代谢途径,影响了整体功能.
科学领域:
- 的微生物学和代谢学.
- 动物营养和生理学
- 类动物生产系统
背景情况:
- 饮食中的能量水平显著影响了在强化反动物生产中的反动物发酵和微生物群落.
- 了解这些影响对于优化畜牧业动物生产率和健康至关重要.
研究的目的:
- 为了研究不同饮食能量水平对小尾汉 (STH) 绵羊肠微生物群体结构,功能和代谢概况的影响.
- 为了阐明不同的可消化能量 (DE) 度如何影响乳头环境及其代谢输出.
主要方法:
- 三十只STH绵羊被以高 (10.8MJ/kgDE),常规 (9.5MJ/kgDE) 和低 (8.2MJ/kgDE) 能量水平的异饮食.
- 用微生物组成和功能的元基因组测序分析含量,并使用非向的代谢组分分析代谢概况.
- 进行了统计分析,以确定饮食组之间的显著差异.
主要成果:
- 高能量的饮食改变了体微生物群落,增加了Bacillota-to-Bacteroidota比率,并丰富了碳水化合物代谢途径.
- 低能耗饮食诱导了"生存模式",富含ABC转运体和核糖体通路,以及胺代谢和TCA循环改变.
- 代谢分析显示,体代谢组发生了显著的重塑,在高能量和低能量组中丰富了不同的途径,包括类固醇激素生物合成和益生素信号传递.
结论:
- 饮食中的能量水平显著改变了肥羊的小羊肠微生物多样性,结构和功能潜力.
- 这些饮食变化深刻地重塑了体的代谢环境,影响了关键的代谢途径.
- 研究结果提供了饮食能量对羊发酵和生产表现的影响的证据.
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