相关实验视频

Updated: Jul 29, 2026

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Published on: November 24, 2012

一种本土的非治疗性纸封闭剂的生物相容性和臭性潜力:使用hDPSCs进行实验室比较分析

Ketaki Turbatmath¹, S Delphine Priscilla Antony¹, Raghunandhakumar Subramanian²

¹Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 600077, Tamil Nadu, India.

Journal of oral biology and craniofacial research

|December 16, 2025

概括

与氧化相比,Api-Therapeutic Pulp Guard (ATPG) 显示出优越的生物相容性,并促进牙生成. 这种新型的辅助治疗剂对再生性内牙治疗具有前景.

科学领域:

生物材料科学生物材料科学
恢复性牙科恢复性牙科
干细胞生物学干细胞生物学

背景情况:

纸封闭剂对于保持牙纸活力至关重要.
评估用于再生性内牙治疗的新生物材料至关重要.
蜂治疗性纸护剂 (ATPG) 是一种本土开发的蜂治疗剂.

研究的目的:

使用人类牙纸干细胞 (hDPSCs) 评估ATPG的细胞相容性.
为了评估ATPG的臭性潜力.
将ATPG与氧化 (RC-Cal) 作为纸封装剂进行比较.

主要方法:

hDPSCs用ATPG和RC-Cal化物进行了处理.
用MTT测定来评估细胞活力.
通过活/死染色来评估膜完整性.
使用qPCR量化了dentinogenic基因表达 (DSPP).

主要成果:

ATPG的细胞活力 (96.52%) 显著高于RC-Cal (84.25%).
活/死试验表明ATPG的膜完整性更好.
在ATPG治疗后,qPCR显示DSPP基因表达增加了3.6倍.

结论:

与氧化相比,ATPG表现出优越的生物相容性和臭性潜力.
作为一种用于再生性内牙科应用的新型剂,ATPG显示出前景.

关键词:

药用治疗性纸保护剂纸保护剂细胞相容性细胞相容性在MTT测试中使用MTT测试.牙产生的差异化差异化 hDPSCss的使用情况.qPCRR 是一个很好的方法.

更多相关视频

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites

Published on: November 9, 2014

Accessing the Cytotoxicity and Cell Response to Biomaterials

Accessing the Cytotoxicity and Cell Response to Biomaterials

Published on: July 8, 2021

相关概念视频

Bioplastics

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...