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阳光暴露,红斑剂量和青少年维生素D度之间的关系:一个横截面的多中心研究
Chidvilas More1, Neha Kajale1,2, Vivek Patwardhan1
1Department of Growth and Pediatric Endocrinology, Hirabai Cowasji Jehangir Medical Research Institute, Pune, IND.
Cureus
|December 16, 2025
概括
维生素D缺乏在印度青少年中很常见,尤其是城市女孩. 更高的阳光照射,特别是在农村地区在冬季,显著改善维生素D状态.
科学领域:
- 营养科学 营养科学
- 公共卫生 公共卫生
- 儿科 儿科 儿科
背景情况:
- 维生素D对于骨健康和平衡至关重要.
- 维生素D缺乏是一个全球性的问题,尤其在印度青少年,尤其是城市女孩中很普遍.
- 对阳光暴露对印度儿童维生素D状况的影响的客观评估是有限的.
研究的目的:
- 检查印度青少年维生素D水平,阳光照射和人体参数之间的关联.
- 根据季节,性别和地理位置 (城市与农村) 调查维生素D状态的变化.
主要方法:
- 这是一项涉及印度六个州545名青少年在冬季和雨季的跨度研究.
- 量化维生素D状态使用25-基维生素D3 (25(OH) D3) 从通过LC-MS/MS的干血斑点.
- 使用聚硫 (PSU) 剂量计标签测量阳光照射,以量化标准红血球剂量 (ED).
主要成果:
- 与农村同行相比,城市青少年的维生素D水平,阳光照射和ED水平较低.
- 农村男孩的维生素D度最高.
- 阳光照射 (ED) 和维生素D水平之间发现了正相关性,特别是在城市地区;BMI/腰围和维生素D之间发现了负相关性.
结论:
- 暴露于阳光是印度青少年维生素D状况的重要预测因素.
- 农村居住和冬季与更高的阳光照射和更好的维生素D水平有关.
- 需要针对城市青少年和女孩进行有针对性的干预,以改善维生素D状态,促进户外活动.
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