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校正后验证扫描对肺内断层瘤错位的影响 立体身体放射治疗中的肺内断层瘤错位
Maddalena M G Rossi1, Barbara Stam1, Iris Walraven1
1Department of Radiation Oncology, the Netherlands Cancer Institute, Amsterdam, Netherlands (the).
Physics and imaging in radiation oncology
|December 16, 2025
概括
纠正后验证 (CBCTVal) 和内弓扫描 (CBCTIA) 在VMAT肺SBRT中显著降低了内断层瘤错位. 忽略这些扫描会增加几何不确定性,需要更大的规划目标体积边缘.
科学领域:
- 辐射瘤学 辐射瘤学
- 医疗成像医学成像
- 癌症治疗方法 癌症治疗方法
背景情况:
- 瘤的位置可以在放射治疗设置的初始成像后转移.
- 精确的瘤向对于有效的肺部立体体辐射疗法 (SBRT) 来说至关重要.
研究的目的:
- 评估CBCT (Val) 后校正验证和CBCT (IA) 内弓扫描对内断层瘤错位的影响.
- 评估VMAT肺SBRT中这些验证步骤的必要性.
主要方法:
- 对167名接受VMAT SBRT治疗的早期肺癌患者的分析.
- 临床协议与模拟协议的比较,忽略了验证扫描 (CBCTNo_Val) 和弧内扫描 (CBCTNo_IFMM).
- 计算瘤错位 (GM,, σ) 和评估与额外纠正相关的因素.
主要成果:
- 在20.4%的分数中,CBCTVal触发了第二次校正;在14.4%的分数中,CBCTIA-1.
- 省略CBCTVal增加了系统 () 和随机 (σ) 错位的27-45%.
- 省略了CBCTVal和CBCTIA,进一步增加了55-90%的,需要增加1-2毫米的PTV利.
结论:
- CBCTVal和CBCTIA-1对于减少VMAT肺SBRT中的几何不确定性至关重要.
- 虽然呼吸幅度和BMI与额外的校正相关,但它们不能可靠地预测患者对验证扫描的需求.
- 这些验证技术对于保持治疗准确性和尽量减少差距至关重要.
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