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除了爬行动物之外:火作为Leishmania (Sauroleishmania) tarentolae的潜在宿主

Alessandro Alvaro¹, Giulia Maria Cattaneo¹, Fabio Bigoni²

¹EntoPar Lab, Department of Biosciences, University of Milan, Milan, 20133, Italy.

International journal for parasitology. Parasites and wildlife

|December 16, 2025

概括

这项研究揭示了Leishmania寄生虫可以感染火 (Urodela),扩大已知的两宿主范围. 分子和形态学方法证实了这些两动物中的Leishmania (Sauroleishmania) tarentolae.

科学领域:

寄生虫学的寄生虫学
两动物生物学
分子生物学分子生物学

背景情况:

莱什曼尼亚寄生虫感染各种脊椎动物,但两动物宿主很少被记录.
对于两动物 (,Anura) 中的Leishmania,只有一个分子记录存在.

研究的目的:

调查Leishmania寄生虫感染Urodelan两动物,特别是火的潜力.
提供第一个分子和形态的证据Leishmania感染在Urodela.

主要方法:

从意大利北部的一个保护区采集了78只火的样本.
对Giemsa染色血液涂抹的形态分析,以寻找类似Leishmania的细胞.
使用Leishmania特异性qPCR和高分辨率化 (HRM) 分析对血液和水抹布进行分子检测.
桑格测序和植物遗传学分析用于寄生虫识别.

主要成果:

在4.48%的血液涂抹中观察到类似莱什曼尼亚的细胞.
寄生虫DNA在7.14%的血液样本和12.12%的克洛亚克擦拭物中检测到.
遗传学分析确定了寄生虫为Leishmania (Sauroleishmania) tarentolae. 这种类型的寄生虫.

结论:

这项研究提供了第一个Leishmania感染在Urodelan两动物 (火) 的证据.
莱什马尼亚 (Sauroleishmania) tarentolae可以感染火,扩大莱什马尼亚已知的宿主范围.
乌罗德兰两动物可能在Leishmania寄生虫的生态和传播中发挥着被忽视的作用.

关键词:

两动物两动物火焰沙兰德是一个火焰沙兰德.莱什曼尼亚 (Leishmania) 是一种病.莱什曼尼亚斑虫 (Leishmania tarentolae) 是一种斑虫.

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