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印度宫癌负担:一项描述性的流行病学研究和政策见解

Khushwant Singh¹, Ashoo Grover¹, Kavitha Dhanasekaran¹

¹Division of Delivery Research, Indian Council of Medical Research (ICMR), Ministry of Health & Family Welfare (MoHFW), Govt. of India, Ansari Nagar, New Delhi 110029, India.

Global epidemiology

|December 16, 2025

概括

宫癌仍然是一个重大的全球卫生挑战,特别是在印度,由于查覆盖率低,人乳头瘤病毒 (HPV) 疫苗接种有限. 迫切需要改变政策,实施HPV-DNA测试和疫苗接种计划,以减少疾病负担.

科学领域:

流行病学流行病学
全球健康全球健康
在瘤学瘤学.

背景情况:

子宫癌是全球主要的健康问题,不成比例地影响低收入和中等收入国家 (LMICs).
人类乳头瘤病毒 (HPV) 疫苗接种和查是有效的预防策略,但LMICs面临实施挑战.
作为一个主要的LMIC国家,印度在预防和控制宫癌方面面临重大障碍.

研究的目的:

分析世卫组织各地区的宫癌负担,重点关注印度.
评估宫癌死亡的趋势和印度国家查政策的影响.
确定导致印度持续存在子宫癌的关键因素.

主要方法:

一项观察性,描述性的流行病学研究,使用来自GLOBOCAN 2022,全球疾病负担 (GBD) 和全球卫生观察站 (GHO) 的数据.
使用GBD数据进行了印度特定的州级分析.
结点回归被用来评估死亡趋势,并对比分析检查了印度2016年宫癌政策的影响.

主要成果:

东南亚地区 (SEARO) 的子宫癌发病率和死亡率排名第二,印度占这一负担的65%以上.
印度的全国查覆盖率非常低 (30-49岁妇女的比例为1.9%),宫癌死亡率呈上升趋势.
虽然自2016年以来死亡率的加快速度已经放缓,但并没有逆转,这表明需要更有效的干预措施.

结论:

印度宫癌的高负担是由于查率低,依赖主观查方法,以及HPV疫苗接种覆盖率不足.
其他国家的成功策略包括基于HPV的查和疫苗接种,突出显示印度需要采用类似方法.
政策转向HPV-DNA测试与自我抽样和全面的国家HPV疫苗接种计划对于有效制印度子宫癌至关重要.

关键词:

意识意识意识意识宫癌是发生在宫癌的原因之一.宫癌流行病学研究这是一个HPVHPVHPV.疫苗接种疫苗接种疫苗接种发生率和死亡率.小微创新型国家和地区 (LMIC)塞阿罗 (SearO) 是一个查指南查指南通过 VIA 通过 VIA 世界卫生组织WHOWHO

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