[在COVID-19感染后,生育年龄男性的荷尔蒙状况和精子参数的评估]
G Antonov A1, I Gamylin K1, V Gordeev V1
1Far Eastern State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia.
Urologiia (Moscow, Russia : 1999)
|December 16, 2025
概括
COVID-19可能会影响男性生殖健康,导致丸激素和精子运动率的暂时下降. 在感染后的三个月内,恢复显示了这些参数的显著改善.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 传染性疾病 传染性疾病
- 安德罗学与人类学
背景情况:
- 后COVID综合征会影响多个器官,包括男性生殖系统.
- 在COVID-19后的长期生殖并发症没有得到充分记录.
- 评估COVID后对男性生殖功能的影响具有临床意义.
研究的目的:
- 在COVID-19康复后,评估生殖年龄男性的荷尔蒙状况.
- 在长期COVID-19康复后评估男性的精液参数.
- 调查COVID-19严重程度对生殖结果的影响.
主要方法:
- 对120名21至44岁的男性进行前性研究,分为肺炎和ARVI组.
- 在发病后的第15天和第90天收集了外周血液和精液样本.
- 分析了总 (TT),FSH,LH,益生菌素,雌激素和SHBG水平.
主要成果:
- 总丸激素在第15天下降 (46%的肺炎,17%的ARVI),但在第90天增加 (20%的肺炎,33%的ARVI).
- 15日SHBG水平升高 (24-25%),90日保持高水平 (11-16%),随着时间的推移显著下降.
- 精子总运动率在第15天和第90天下降,主要是由于渐进性运动率下降,但在第90天显著改善.
结论:
- 在男性中,COVID-19显著改变了和SHBG水平,在三个月内观察到恢复趋势.
- 精子运动和形态表现出最初的减少,但在COVID-19后的第三个月显著改善.
- 这些发现强调了在COVID-19感染后监测男性生殖健康的重要性.
相关概念视频
01:23Infertility in Males
509
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
509
01:20Disorders of the Male Reproductive System
3.9K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
3.9K
01:41Spermatogenesis
121.3K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
121.3K
01:28Menopause
3.5K
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
3.5K
01:22Sperm Structure and Semen Composition
10.0K
During ejaculation, males release around 2-5 milliliters of semen, which is a complex mixture of mature sperm and various fluids produced by accessory glands. The mature sperm cells measure approximately 60 micrometers in length and consist of a head, neck, midpiece, and tail. The head is flattened and tapered, measuring about 4 to 5 micrometers in length. It contains a nucleus with condensed chromosomes and an acrosome, a cap-like structure filled with enzymes essential for penetrating the...
10.0K
01:26Testosterone: Functions and Regulation
2.0K
The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
2.0K