[前列腺癌与低性男性心血管疾病的关系]
D Anosov A1,2,3, E Efremov M1,2,3, L Medvedev V1,2,3
1Research Institute Regional Clinical Hospital 1 Prof. S.V. Ochapovsky, Krasnodar, Russia.
Urologiia (Moscow, Russia : 1999)
|December 16, 2025
概括
心血管疾病 (CVD) 经常在患有前列腺癌 (PCa) 的异性恋男性中被诊断为患有前列腺癌 (PCa),具有特定的疾病,如心痛和失脂症,与PCa的关联比与前列腺增生 (PH) 更强. 对心血管疾病-PCa机制的进一步研究可能会降低PCa风险.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 心脏病学 心脏病学
- 在瘤学瘤学.
背景情况:
- 心血管疾病 (CVD) 和前列腺癌 (PCa) 是患病和死亡的普遍原因.
- 以前的研究表明,低性活动和PCa发展之间存在联系.
- 澄清心血管疾病和PCa之间的关系对于了解疾病病因和风险因素至关重要.
研究的目的:
- 为了确定心血管疾病 (CVD) 诊断的频率,在接受前列腺癌 (PCa) 支臂治疗的异性恋男性中.
- 为了比较患有PCa的男性和患有前列腺增生 (PH) 的男性心血管疾病的患病率.
主要方法:
- 一项涉及148名新诊断PCa的男性 (I组) 和99名前列腺增生 (PH) 的男性 (II组) 的研究.
- 根据临床建议,使用罗斯托夫问卷评估男性性取向并诊断心血管疾病.
- 测量血清总水平的测量.
主要成果:
- 超过50%的PCa男性表现出低性活动和降低丸激素水平.
- 与PH相比,在PCa的男性中,特定的心血管疾病,如胸痛和脂质失调明显更常见.
- 虽然一些心血管疾病没有显示差异,但其他如慢性心力衰竭在PH组中更为普遍.
结论:
- 该研究确定了不同心血管疾病和PCa之间的不同频率和关联.
- 在CVD-PCa和CVD-PH关系中存在显著差异,这表明有不同的潜在机制.
- 调查CVD和PCa之间的联系机制有望为开发减轻PCa风险的策略提供希望.
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