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精子分离的自由离心机分类改善了细胞内的精子注射结果:系统性审查和元分析

Fatemeh Dehghanpour^1,2, Mohammad Ali Khalili^1,2, Amin Salehi-Abargouei^3,4,5

¹Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Clinical and experimental reproductive medicine

|December 16, 2025

概括

自由离心机分类 (FCS) 改善了用于细胞内注射 (ICSI) 的精子质量,显著提高了植入和怀孕率. 这种技术增强精子,以获得更好的辅助生殖技术结果.

科学领域:

生殖医学生殖医学
安德罗学与人类学
辅助生殖技术辅助生殖技术

背景情况:

精子制备对于辅助生殖技术 (ART) 的成功至关重要.
传统的精子分离方法可能会导致氧化应激和细胞损伤.
自由离心机分类 (FCS) 提供了一个潜在的替代方案,以尽量减少精子创伤.

研究的目的:

系统地审查和元分析FCS对细胞内精子注射 (ICSI) 结果的影响.
将FCS与ART中的传统精子制备技术进行比较.

主要方法:

在主要数据库 (PubMed,Scopus,Web of Science,Cochrane) 进行系统的文献搜索.
根据PRISMA-P指南进行的元分析.
用于研究选择的PICOS方法;主要结果包括受精率 (FR),高质量的胚胎率,植入率 (IR) 和临床怀孕率 (CPR).

主要成果:

三项研究被纳入了元分析.
FCS产生的精子具有卓越的生物质量.
带有FCS的ICSI显著增加了植入率 (IR) 和临床怀孕率 (CPR).
没有观察到受精率 (FR) 的显著差异.

结论:

自由离心机分类 (FCS) 是准备ICSI精子的一个有前途的技术.
FCS提高了精子质量,从而改善了ICSI周期中的生殖结果.
进一步的研究可能会验证FCS作为标准ART程序.

关键词:

离心机离心机离心机的使用方法密度梯度内细胞质精子注射精子注射有助于生殖技术的生殖技术.精子动物 (Spermatozoa) 是一种精子.

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