压力控制通风-保证体积对肺氧化功能的影响 在接受非冠状动脉旁路移植的患者中
Xiao-Yong Wei1, Fang-Hua Chen2, Jun Li1
11 Department of Anesthesiology and Perioperative Medicine,General Hospital of Ningxia Medical University,Yinchuan 750004,China.
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
|December 16, 2025
概括
压力控制通风-保证体积 (PCV-VG) 在非抽动冠状动脉旁路移植 (OPCABG) 期间改善肺氧化. 这种通风策略降低了气道压力,与体积控制通风 (VCV) 相比,改善了氧化指数.
科学领域:
- 麻醉学和外科手术期间的医学.
- 心胸外科手术 心胸外科手术
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 无冠状动脉旁路移植 (OPCABG) 需要仔细管理外科手术期间的肺功能.
- 优化通风策略对于维持充足的氧化和减少心脏手术患者的肺部并发症至关重要.
研究的目的:
- 评估压力控制通风-保证体积 (PCV-VG) 对经过OPCABG的患者外科手术期间肺氧化的影响.
- 在这个患者群体中,将PCV-VG与传统的体积控制通风 (VCV) 进行比较.
主要方法:
- 一项随机对照试验,涉及40名接受选择性OPCABG的患者,分为VCV或PCV-VG组.
- 呼吸系统参数包括气道峰值压力,平均气道压力,平原气道压力和动态合规性在多个手术内时间点记录.
- 氧化指数,如氧气的气膜-动脉部分压差 (PA-aDO2),氧化指数 (OI) 和呼吸指数 (RI) 在手术内和术后被测量.
主要成果:
- 与VCV组相比,PCV-VG组在特定的手术内阶段显示出明显较低的气道峰值压力,平均气道压力和平原气道压力.
- PCV-VG导致氧化的改善,证实了降低PA-aDO2和RI,并增加了OI,特别是在后期的手术阶段和术后.
- PCV-VG组的患者经历了更短的内管内置时间和更短的重症监护室 (ICU) 停留时间.
结论:
- 压力控制通风-保证体积 (PCV-VG) 在增强OPCABG患者的外科手术期间肺氧化方面优于体积控制通风 (VCV).
- 通过改善肺功能和潜在地减少术后恢复时间,PCV-VG可能有助于改善患者的治疗结果.
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