在囊内的形瘤 Xanthoma 囊内的 Hidradenitis Suppurativa 的
Deaquan Nichols1, Aref Moshayedi2, Ja Hea Gu3
1School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Journal of cutaneous pathology
|December 16, 2025
概括
一种罕见的皮肤病变 - - Verruciform xanthoma (VX) - - 在一个患有补性腺炎 (HS) 的患者的卵泡囊内发现. 这表明HS的慢性炎症可能会引发二次VX类变化.
科学领域:
- 皮肤病学 皮肤病学
- 组织病理学 组织病理学
背景情况:
- 形黄瘤 (Verruciform xanthoma,简称VX) 是一种罕见的病变,通常在口腔或生殖器粘膜中发现.
- VX的特征是状上皮质增生和泡状囊细胞.
- 维克斯已经与炎症性皮肤病 (如平坦和硬化等) 相关.
研究的目的:
- 报告发生在 hidradenitis suppurativa (HS) 的背景下出现的第一个记录下来的形黄素瘤 (VX) 病例.
- 探索HS中慢性炎症与二次VX类变化的发展之间的潜在联系.
主要方法:
- 对一个患有Hurley 3期HS的患者手术切除样本的组织病理学检查.
- 从同一个患者之前的HS标本的回顾性审查.
主要成果:
- 组织病理学揭示了一种状层的卵泡囊,与HS相一致.
- 大约10%的囊内表现出VX特征的特征,包括乳头瘤性和泡性巨细胞.
- 以前的HS标本没有表现出类似VX的变化.
结论:
- 这种病例扩大了已知的HS组织学谱.
- 在HS的慢性炎症可能会在卵泡囊内促进二次形形变化.
- 识别HS中的VX类变化对于避免误诊至关重要,特别是状细胞癌.
相关概念视频
Skin Cancer
5.7K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.7K
Skin Diseases and Disorders
5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
Assessment of the Rectum and Anus
1.0K
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
1.0K
Papillary Dermis
5.3K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
5.3K
Inflammatory Bowel Disease II: Crohn's Disease
909
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
909
Urologic Endoscopic Procedure: Cystoscopic Examination
1.9K
Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...
1.9K


