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视网膜氧气动力学和血流在不同程度近视的特征

Xuan Ding^1,2,3,4,5, Jiayi Hu^1,2,3,4,5, Yong Ma^1,2,3,4,5

¹Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.

Investigative ophthalmology & visual science

|December 16, 2025

概括

视网膜血流和氧气水平随着近视的增加而下降. 动脉氧和度的显著下降发生在高近视,特别是轴长超过25.45毫米.

科学领域:

眼科医生眼科眼科
视网膜成像视网膜成像
血管生理学血管生理学

背景情况:

近视是一个日益严重的全球健康问题.
了解近视的视网膜血管变化对于预防并发症至关重要.

研究的目的:

为了研究视网膜氧气动力学和不同近视严重程度的血液流动.
确定与这些变化相关的因素.

主要方法:

包括132名非近视,轻度至中度近视和高近视的参与者.
使用多式眼功能成像和分析系统评估视网膜氧气和血液流动.
使用概括估计方程和受限立方线分析分析数据.

主要成果:

视网膜血管直径随着近视的严重程度逐渐减少.
静脉血流速度和视网膜血流减少在轻度至中度和高近视.
动脉氧和仅在高近视 (轴长≥25.45毫米) 中显著下降.
轴长与氧和和血流参数独立相关.

结论:

即使在近视的早期阶段,视网膜血管功能也会受到损害.
显著的动脉氧气不和与高近视的较长轴长度有关.
这些发现为高近视的 fundus 血管并发症提供了洞察力.

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