Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Assessment of apical radial pulse01:25

Assessment of apical radial pulse

1.6K
Apical-Radial (A-R) Pulse Assessment
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation
1.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Patient-Reported Outcomes in Masculinizing Gender-Affirming Chest Surgery: Validation of the GENDER-Q Chest Scales.

The British journal of surgery·2026
Same author

Strike a pose, and…virtual visit? Examining virtual vs. in-person consultations for gender affirmation surgery.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2026
Same author

Economic Valuation and Disability Averted After Cleft Lip and/or Palate Repair in Botswana From 2018 to 2022.

The Journal of craniofacial surgery·2026
Same author

Bilateral Cleft Lip Repair With and Without Primary Rhinoplasty: Comparing Two-Year Aesthetic and Anthropometric Outcomes.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association·2026
Same author

Mandibular Distraction Osteogenesis as Paradigm Shift for Treatment of Tongue-Based Obstructive Apnea: Results of a 16-Year, Hospital-Wide Intervention Trial.

Plastic and reconstructive surgery·2026
Same author

Longitudinal patient-reported outcomes of vaginal dilation after penile inversion vaginoplasty.

The journal of sexual medicine·2026

相关实验视频

Updated: May 5, 2026

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
04:05

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis

Published on: June 30, 2023

2.7K

APERT严重程度尺度:在Apert综合征中进行风险分层的一个定量工具.

Allison C Hu1, Philip D Tolley, Nicholas A Han

  • 1Division of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA.

Plastic and reconstructive surgery
|December 16, 2025
PubMed
概括

一个新的定量严重程度尺度,APERT评分,有助于分类阿珀特综合征的复杂性. 该工具有助于客观风险分层和个性化治疗计划,为患有这种罕见疾病的患者.

更多相关视频

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

734
Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment
08:25

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Published on: December 6, 2024

821

相关实验视频

Last Updated: May 5, 2026

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
04:05

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis

Published on: June 30, 2023

2.7K
Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

734
Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment
08:25

Polar Histogram Visualization of Acute Stress Disorder Scale Scores for Comprehensive Clinical Assessment

Published on: December 6, 2024

821

科学领域:

  • 医学遗传学 医学遗传学
  • 儿科手术 儿科手术
  • 头骨和面部外科手术

背景情况:

  • 阿珀特综合征是一种罕见的遗传性疾病,其特征是肌缩症,中脸过度成形和突触,通常源于FGFR2突变.
  • 它的多系统性和缺乏标准化指导方针给诊断和治疗带来了挑战.
  • 为了客观的风险分层和个性化护理,需要一个定量严重程度的尺度.

研究的目的:

  • 引入和验证阿珀特综合征的定量严重程度等级.
  • 建立一个客观风险分层和个性化治疗计划的工具.

主要方法:

  • 在1988年至2024年期间接受治疗的阿珀特综合征患者的回顾性审查,纳入标准是最后一次随访时的年龄≥11岁.
  • 基于文献和临床数据,开发了一个五个领域的严重程度尺度 (气道,压力,眼睛,逆转,脑 - APERT).
  • 使用手术前临床照片和文档进行的评分.

主要成果:

  • 37名患者符合纳入标准;平均随访年龄为17.0±5.0岁,平均4.4±2.2次面手术.
  • APERT评分在5-15之间,将患者分为轻度 (5-7),中度 (8-11) 和严重 (12-15) 组.
  • 较高的APERT分数与手术频率增加有很强的相关性 (r=0.851,p<0.001),分数≥9预测≥6次具有高灵敏度和特异性的手术.

结论:

  • APERT评分是第一个对阿珀特综合征严重程度的定量分类.
  • 该得分与表型负担和手术量相关,可能改善临床沟通和治疗规划.
  • 这种尺度为基于风险的管理和在阿珀特综合征护理中的机构比较提供了有价值的工具.