描述跨性别和非二进制患者的炎症性肠病的医疗保健差异,利用和趋势:基于人口的研究
Andrew Suchan1, Lara Chaaban2, Lynn Kobeissi2
1Division of Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
变性人和非二进制 (TGNB) 个体患有炎症性肠病 (IBD) 经历了更多的并发症和更少的治疗. 激素替代疗法 (HRT) 在这个人群中没有恶化IBD的结果.
科学领域:
- 胃肠病学 胃肠病学
- 健康差异 在健康上的差异
- 在LGBTQ+健康方面
背景情况:
- 跨性别和非二进制 (TGNB) 个人面临着严重的医疗保健差异.
- 对于TGNB群体的炎症性肠病 (IBD) 患病率和护理情况知之甚少.
- TGNB个体占美国人口的0.5%至0.6%.
研究的目的:
- 为了描述TGNB成年人中的IBD患病率.
- 为了比较TGNB与cisgender的IBD患者.
- 评估激素替代疗法 (HRT) 对TGNB IBD患者的影响.
主要方法:
- 使用TrinetX数据库进行分析.
- 比较人口统计,并发症,实验室标志物和医疗保健利用情况.
- 检查了IBD治疗模式和不良事件 (心血管,血栓).
主要成果:
- 在TGNB成年人中,IBD患病率为克罗恩病的0.508%,性结肠炎的0.448%.
- TGNB IBD患者年轻,患有更多的胃肠道/精神疾病并发症,医疗保健利用率更高.
- TGNB IBD患者接受的内镜和向治疗较少;HRT与更差的结果无关.
结论:
- TGNB IBD 患者表现出更大的并发症负担,尽管增加了医疗保健接触,但接受的干预措施较少.
- 激素替代疗法 (HRT) 与不良IBD结果或并发症无关.
- 这些发现强调了TGNB个体在IBD护理中的严重差异,需要进一步研究.
更多相关视频
09:44Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
Published on: October 14, 2025
08:02Visualization of Estrogen Receptors in Colons of Mice with TNBS-Induced Crohn's Disease using Immunofluorescence
Published on: March 12, 2020
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
