在结直肠内镜下粘膜解剖后口服摄入的时间:一种倾向性得分匹配研究
Yasuyuki Tanaka1, Yumi Tokubayashi2, Kentaro Aoki2
1Department of Gastroenterology and Hepatology, Kyoto Katsura Hospital, 17 Yamada-Hirao, Nishikyo-Ku, Kyoto, 615-8256, Japan. yasutnk5526@yahoo.co.jp.
在结直肠内镜下粘膜解剖 (ESD) 后,在术后的第一天恢复口服是安全的和可行的. 早期食并没有增加不良事件,并且与延迟摄入相比,体重减轻较少.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 临床营养学 临床营养学
背景情况:
- 在结直肠内镜下粘膜解剖 (ESD) 后恢复口服的最佳时间尚未确立.
- 目前的做法各不相同,影响患者的康复和结果.
研究的目的:
- 评估在结直肠ESD后,在术后一天 (POD1) 和POD2开始口服的安全性和可行性.
- 为了比较早期和晚期口服摄入组之间的不良事件率和术后症状.
主要方法:
- 220名接受结直肠ESD (2017-2024) 的患者的回顾性审查.
- 每组58名患者的倾向性得分匹配 (1:1) (POD 1与POD 2摄入量).
- 主要结局:在30天内与手术相关的不良事件;次要结局:症状和体重变化.
主要成果:
- 不良事件发生率在各组之间是可比的 (例如,出血,穿孔).
- 在术后发烧或腹痛方面没有显著差异.
- 早期的口服摄入与POD3的体重减轻显著减少.
结论:
- 结肠直肠ESD后的早期口服 (POD 1) 是为选定的患者提供安全和可行的选择.
- 需要进一步的前性研究来确认早期养方案的常规采用.
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