基于超声波的成像对黑色素瘤的积极监测至关重要吗?
Natalie N Chakraborty1,2, Maira Bhatty2, Kevin G Zablonski2,3
1Department of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Annals of surgical oncology
|December 16, 2025
概括
对哨戒淋巴结阳性黑色素瘤的积极监测显示,对节点超声波 (US) 的不一致的坚持. 截面成像在检测复发方面比美国更有效,这表明需要更新当前的监控协议.
科学领域:
- 黑色素瘤研究研究
- 在瘤学瘤学.
- 医学成像医学成像
背景情况:
- 里程碑式的试验支持通过节点超声波 (US) 积极监测哨兵淋巴结 (SLN) 阳性黑色素瘤,提供相当于完成淋巴结剖析 (CLND) 的结果.
- 现实世界对美国监视的坚持是不一致的.
- 美国在现代横截面成像技术中扮演的角色需要定义.
研究的目的:
- 评估SLN阳性黑色素瘤患者遵守指导方针一致的监测.
- 评估复发检测模式和活检的诊断产量.
- 为了确定监控遵守的预测因素.
主要方法:
- 对240名SLN阳性成年黑色素瘤患者 (2017-2023) 的回顾性队列研究.
- 评估了切割后2年的监测遵守情况.
- 使用多变量逻辑回归来识别坚持的预测因素.
主要成果:
- 92.9%的患者计划接受主动监测,55.3%遵守美国标准,而88.0%接受了横截面成像.
- 截面成像检测到64.9%的复发,明显高于美国 (7.8%).
- 晚些时候的诊断预测了美国的坚持;年龄较大和头部瘤预测了较低的坚持.
结论:
- 截面成像显示出优越的性能和一致性,与节点盆地美国相比.
- 研究结果表明,需要现代化黑色素瘤监测计划,以尽量减少过度检测.
- 在当前实践中,严格遵守MSLT-II试验协议的重新评估是有必要的.
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