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Updated: Jun 26, 2026

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
10:50

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裂谷热病毒包裹蛋白的冷EM结构与强大的中和抗体复合在一起

Linjing Zhang1,2,3, Kaiwen Meng1,2,3, Ye Xiang1,2,3

  • 1Beijing Frontier Research Center for Biological Structure, Center for Infection Biology, School of Basic Medical Sciences, Tsinghua University, Beijing 100084, People's Republic of China.

Proceedings of the National Academy of Sciences of the United States of America
|December 16, 2025
PubMed
概括

裂谷热病毒 (RVFV) 糖蛋白 Gn 和 Gc 的结构细节使用冷EM揭示出来. 发现一种中和抗体 (RVFV-140) 通过稳定 GnGc 六合体的预注射构造来阻止病毒的进入.

关键词:
裂谷热病病毒病毒抗体中和机制的抗体中和机制化-EM结构的结构.葡萄糖蛋白是一种葡萄糖蛋白质.

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