皇家果治疗绝经后症状:一个系统的审查和元分析
Sarah Dagostin Ferraz1, Luana Stangherlin1, Tamy Colonetti1
1Laboratory of Translational Biomedicine, Universidade do Extremo Sul Catarinense, Santa Catarina, Brazil.
概括
与安慰剂相比,皇家果 (RJ) 补充剂显著改善了女性的更年期症状. 这种天然选择对骨和泌尿生殖系统健康有好处,特别是对于那些避免激素治疗的人来说.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 营养科学 营养科学
- 妇女健康 妇女健康
背景情况:
- 更年期涉及激素停止,导致症状往往用激素治疗治疗.
- 激素疗法有禁忌,需要替代治疗来缓解更年期症状.
- 皇家果 (RJ) 被探索为一种潜在的非激素替代品,但证据有限.
研究的目的:
- 系统地评估皇家果 (RJ) 补充剂在缓解绝经后症状中的有效性.
- 评估RJ对更年期妇女泌尿生殖系统健康和生活质量的影响.
主要方法:
- 在主要数据库 (PubMed,LILACS,Embase,Cochrane Library) 进行了全面的文献搜索,使用与皇家果和更年期相关的关键词.
- 如果这些研究评估了对更年期后症状的干预措施,并专注于生殖尿路结果和生活质量,则将这些研究纳入.
- 六项随机对照试验涉及471名绝经后妇女,在2011年至2021年之间发表,被纳入了元分析.
主要成果:
- 与安慰剂相比,皇家果 (RJ) 补充剂在绝经后症状中显著改善.
- 在312名参与者的两项研究中,效应大小中等 (SMD=0.73,95% CI 0.50-0.96,P <0.00001),没有异质性 (I2=0%).
- 证据质量被评为中等.
结论:
- 皇家果 (RJ) 补充剂为管理更年期症状提供了一个可行的非激素治疗选择.
- 在更年期期间,RJ可能会支持骨和生殖尿道健康.
- 对于无法或不愿意使用常规激素治疗的女性来说,它特别有益.
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