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辅助蛋白MRAP2直接与黑色素-3受体相互作用,以增强信号传递

Aqfan Jamaluddin1,2, Rachael A Wyatt1,2, Joon Lee3

  • 1Department of Metabolism and Systems Science, University of Birmingham, Birmingham B15 2TT, UK.

Science signaling
|December 16, 2025
PubMed
概括

黑色皮质素-2受体辅助蛋白2 (MRAP2) 调节黑色皮质素-3受体 (MC3R),影响能量稳态. 与肥胖相关的MRAP2变体损害了这一关键的MC3R信号通路.

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