产前成像预测,新生儿患有先天性肺形需要早期干预
Jasmine Lee1, Sharon Joseph1, Kelsey Pape2
1Department of Surgery, Section of Pediatric Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
The Journal of surgical research
|December 16, 2025
概括
产前超声波和MRI可以预测先天性肺形 (CLMs) 的婴儿早期干预的需要. 超声波上较大的病变大小和生长是预测新生儿患有CLM的结果的关键指标.
科学领域:
- 新生儿护理 新生儿护理
- 儿科放射学 儿科放射学
- 有先天性异常.
背景情况:
- 先天性肺形 (CLMs) 呈现出一系列的新生儿结局,从无症状呈现到严重的呼吸困扰.
- 产前成像技术的进步改善了CLM的检测,但预测临床严重程度仍然具有挑战性.
研究的目的:
- 为了比较产前超声波 (美国) 和磁共振成像 (MRI) 标记,用于预测产前诊断的CLMs的婴儿的早期产后结果.
- 识别关键的成像特征,表明需要早期干预的新生儿与CLMs.
主要方法:
- 进行胎儿MRI (2002-2023) 的产前诊断的CLM的新生儿的回顾性审查.
- 与对照组相比,需要早期手术或先进呼吸支的患者的比较.
- 产前US和MRI标记的单变量和多变量分析,以预测早期干预.
主要成果:
- 早期干预的重要预测因素包括第二季度美国病变大小,随访美国病变生长以及第二季度MRI病变量.
- 美国和MRI都显示出适度的预测能力 (AUC分别为0.77和0.72).
- 美国的病变大小是早期干预的最重要的预测因素 (OR 1.022,P=0.019).
结论:
- 产前US和MRI特征,特别是尺寸和生长,与患有CLM的新生儿早期干预风险增加有关.
- 超声波病变大小是一个特别强大的预测器,需要早期干预的CLMs.
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