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针对糖免疫检查点封锁的抗体 - 乳素仿真体

Jessica C Stark1,2,3, Melissa A Gray4, Itziar Ibarlucea-Benitez5

  • 1Department of Biological Engineering, MIT, Cambridge, MA, USA. jcstark@mit.edu.

Nature biotechnology
|December 16, 2025
PubMed
概括

新的抗体 - 莱克嵌合体 (AbLecs) 通过阻断葡萄糖免疫检查点,为癌症免疫疗法提供了一种新方法. 这些工程分子增强了对瘤的免疫细胞活性,在其他治疗方法失败的地方显示出希望.

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Antibodies, or immunoglobulins, are critical players in the immune system's arsenal against invading pathogens. Produced by B cells and plasma cells, their primary role is to detect and bind to specific antigens, molecules found on the surface of pathogens like bacteria or viruses. Beyond antigen recognition, antibodies perform several vital functions that contribute to immune defense.
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