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Updated: Jan 8, 2026

Detection of Microregional Hypoxia in Mouse Cerebral Cortex by Two-photon Imaging of Endogenous NADH Fluorescence
12:03

Detection of Microregional Hypoxia in Mouse Cerebral Cortex by Two-photon Imaging of Endogenous NADH Fluorescence

Published on: February 21, 2012

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大胆的信号变化可以在人类皮层中反对氧化代谢

Samira M Epp1,2,3, Gabriel Castrillón1,2,4, Beijia Yuan5

  • 1Institute of Neuroradiology, Uniklinikum Erlangen, Friedrich-Alexander-Universitat Erlangen-Nurnberg, Erlangen, Germany.

Nature neuroscience
|December 16, 2025
PubMed
概括

功能性MRI (fMRI) 依赖于血液氧气水平依赖 (BOLD) 信号,但研究结果显示,约40%的信号涉及逆向的氧化代谢,挑战其解释. 定量fMRI可能提供更可靠的神经元活动评估.

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Simultaneous Electroencephalography, Real-time Measurement of Lactate Concentration and Optogenetic Manipulation of Neuronal Activity in the Rodent Cerebral Cortex10:45

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