通过全球化,教育和创新促进MID3的变化
Douglas W Chung1, Sihem Ait-Oudhia2
1Certara Inc, Radnor, PA, USA. doug.chung@certara.com.
Journal of pharmacokinetics and pharmacodynamics
|December 16, 2025
概括
基于模型的药物发现和开发 (MID3) 需要全球合作和多样化的科学投入来加速创新. 拥抱全球化,教育和多样化的数据,确保为所有患者提供公平,有效的药物.
科学领域:
- 制药指标 (Pharmacometrics) 是一个指标.
- 药物开发 药物开发
- 翻译科学 翻译科学
背景情况:
- 制药行业正在不断发展,基于模型的药物发现和开发 (MID3) 准备加速创新.
- 实现MID3的全部潜力需要全球合作,加强教育和科学进步.
- 药物开发的进步需要具有包容性的方法,包括多样化的患者数据,并培养全球科学界.
研究的目的:
- 强调全球化在药量测量合作中的关键作用.
- 为全球人才库强调平等获得教育和培训的重要性.
- 为了证明多样性如何推动药物开发的定量方法的创新.
主要方法:
- 讨论不同患者群体 (儿科,孕妇) 的整合.
- 促进包容性的科学环境和全球合作.
- 倡导公平获得药量学教育和培训.
主要成果:
- 全球化扩大了跨越边界和文化的药物测量合作.
- 来自多元科学界的多样化的观点和专业知识带来了更丰富的见解.
- 扩大的多样性鼓励采用先进的定量方法 (PK/PD,PBPK,QSP/T,AI).
结论:
- 整合全球化,教育和创新是推动MID3的关键.
- 多方面的方法确保了公平的结果,并加速了有效药物的开发.
- 药量计学社区可以催化显著的变化,使所有患者受益.
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