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Updated: Jan 8, 2026

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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用LC-MS/MS和其临床前药理动力学评估在老鼠血中开发polmacoxib的生物分析方法

Aniket Sohani1, Shubham Debaje2, Kajal Guleria2

  • 1Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Mohali, India.

Bioanalysis
|December 17, 2025
PubMed
概括

一种新的LC-MS/MS方法准确地量化了大鼠血中的polmacoxib. 这种验证的测定对于polmacoxib的临床前药理动力学研究至关重要.

关键词:
在 LCMS/MS 中使用.波尔马可克西布 (Polmacoxib) 是一种药物.生物等价性 生物等价性染色体学 染色体学 染色体学药物动力学 药物动力学

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