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Updated: Jan 8, 2026

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对牙周炎严重程度和进展的全基因组关联研究

Flavia Teles1,2, Ganesh Chandrasekaran3, Lynn Martin1

  • 1Department of Basic & Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Journal of periodontology
|December 17, 2025
PubMed
概括

这项全基因组关联研究确定了两个关键基因,SUMO2P2和CUBN,与牙周病进展有关. 这些发现增强了我们对牙疾病遗传易感性的理解.

关键词:
疾病的进展 疾病的进展基因 基因 基因 基因全基因组关联研究研究.牙周炎是指牙周炎的一种疾病.现象型 现象型 是一种现象型.多态性,单核酸,单核酸.易感性 易感性 易感性

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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