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乙型肝炎病毒血清标志物作为北印度患者查的未满足需求

Sana Irfan¹, Pankaj Kumar², Kumari Seema²

¹Department of Microbiology, MGM Medical College, Jamshedpur, Jharkhand, India.

Journal of family medicine and primary care

|December 17, 2025

概括

大多数乙型肝炎病毒 (HBV) 感染是慢性且无症状的. 针对HBV血清标志物和HIV等共感染的例行查对于有效的管理和传播控制至关重要.

科学领域:

肝病学肝病学是一种肝病学.
病毒学病毒学
公共卫生公共卫生

背景情况:

慢性乙型肝炎是全球重要的健康问题.
血清标记对于诊断和管理乙型肝炎病毒 (HBV) 感染至关重要.
有效的监测和治疗规划取决于识别这些标记物.

研究的目的:

在HBsAg阳性个体中分析HBV血清标志物的患病率.
研究与人类免疫缺陷病毒 (HIV),C型肝炎病毒 (HCV) 和D型肝炎病毒 (HDV) 共同感染率.

主要方法:

血清标志物 (HBsAb,HBcAb,HBeAg,anti-HBe,HBcIgM) 在481名HBsAg阳性患者中使用化学发光免疫检测进行了分析.
在这些患者中评估了HIV,HCV和HDV的同时感染.
从RIMS,Ranchi.的19607名查患者收集了数据.

主要成果:

在351名血清标志物分析的患者中,98.29%患有慢性HBV感染,80.05%无症状.
在23.36%的病例中检测到HBeAg,在66.66%的病例中检测到抗HBe.
在6.26%的患者中观察到HIV同时感染,主要在31-40岁年龄组.

结论:

大多数确诊的HBV病例是慢性且无症状的.
很大一部分患者患有并发感染,尤其是艾滋病毒.
建议定期对HBV血清标志物和共感染进行查,以提供治疗指导和减少传播.

关键词:

乙型肝炎抗体 (HBsAb) 是一种乙型肝炎核心抗体 (IgM+IgG) (HBcAb) 的研究.乙型肝炎的包膜抗原 (HBeAg)

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