在老年人中揭露贫血:关于患病率,原因和后果的系统审查
Debashis P Sahoo1, Annu Gupta1, Gwenette A War1
1Department of General Medicine, All India Institute of Medical Sciences (AIIMS), Guwahati, Assam, India.
Journal of family medicine and primary care
|December 17, 2025
概括
贫血影响近28%的老年人,增加死亡率和心血管风险. 无法解释的贫血是一个重要的健康负担,需要有针对性的干预措施.
科学领域:
- 老年学是指老年学的学科.
- 血液学 血液学 血液学
- 公共卫生 公共卫生
背景情况:
- 贫血在老年人 (≥65岁) 中很常见,与更高的疾病,死亡率和生活质量下降有关.
- 现有的有关贫血在老年人中患病率,原因和结果的数据是不够的.
研究的目的:
- 巩固65岁及以上个体贫血患病率,病因和临床结果的证据.
- 为了指导临床实践和未来的研究方向,老年人贫血管理.
主要方法:
- 来自主要数据库的47项研究 (观察性,队列,横截面,综述) 的系统文献综述 (2004-2024年).
- 纳入标准侧重于老年人贫血,其质量通过纽卡斯尔-太华尺度和AMSTAR 2进行评估.
- 使用叙述合成和生物统计分析 (汇总流行率,HRs,ORs,CI),通过I2统计评估异质性.
主要成果:
- 综合贫血患病率为27.8% (95%CI:22.1-33.5),住院患者 (37.4%) 比社区住院 (23.1%) 的老年人高.
- 主要病因包括不明原因的贫血 (34.2%),缺铁性贫血 (27.5%) 和慢性疾病的贫血 (20.1%).
- 贫血显著增加了所有原因的死亡率 (汇总HR:2.85) 和心血管事件 (汇总HR:3.12).
结论:
- 贫血在老年人群中代表着相当大的健康负担.
- 无法解释的贫血特别令人担忧,突出了需要特定的诊断和治疗方法的需要.
- 针对性策略对于管理老年人贫血至关重要,以改善结果.
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