科里尼细菌状体感染性内心炎:一个系统性审查
Minghuan Hong1, Wei Xiang1, Lingyun Kong1
1Cardiovascular Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, People's Republic of China.
Journal of inflammation research
|December 17, 2025
概括
皮质杆菌菌带状传染性内心炎 (CSIE) 是一种严重的疾病,常常被误诊. CSIE的死亡率和手术干预率高于常见的传染性内心炎,需要立即临床治疗.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 微生物学 微生物学
背景情况:
- 皮质细菌 (Corynebacterium striatum,CS) 是感染性内心炎 (IE) 的不常见原因.
- 关于CS感染性内心炎 (CSIE) 的临床模式和进展的文献有限.
- 本研究回顾性地分析了已记录的CSIE案例,以了解其呈现和管理.
研究的目的:
- 为了阐明CSIE的临床表现.
- 分析CSIE的管理策略.
- 将CSIE结果与常见病原体引起的IE进行比较.
主要方法:
- 在主要数据库 (PubMed,CNKI等) 进行系统的电子文献搜索. ) 的情况.
- 从已识别的物品中提取和分析患者级数据.
- 追溯案例系列分析.
主要成果:
- 分析了35篇文章中的38名患者;中位数年龄68岁,63.2%是男性.
- 中枢是受影响最严重的部位 (52.8%);误诊率为28.9%.
- 范科米辛显示有效;41.7%的CS分离物是多药耐药的. 总的死亡率为37.8%.
结论:
- CSIE通常呈现不具体,导致误诊.
- 像16S rRNA和mNGS这样的先进诊断提高了准确性.
- CSIE的外科手术和死亡率高于普通IE,需要提高临床警.
相关概念视频
Endocarditis II: Clinical Features of Infective Endocarditis
371
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
371
Endocarditis I: Introduction
362
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
362
Endocarditis III: Medical Management
197
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
197
Endocarditis IV: Nursing Management
297
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
297
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
443
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
443
Acute Coronary Syndrome III: Diagnostic Studies
197
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
197


