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Updated: Jan 8, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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合成和评估新型的aza-aromatics作为双重5-HT2A和5-HT2C受体对抗剂

Amit Singh Adhikari1, Annu Yadav2,3, Soumen Pandit1

  • 1Medicinal & Process Chemistry Division, CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031, Uttar Pradesh, India.

ACS medicinal chemistry letters
|December 17, 2025
PubMed
概括

研究人员确定了新的双重5-HT2A/5-HT2C激动剂,包括化合物3ci,用于潜在的中枢神经系统疾病治疗. 这些化合物显示出作为非幻觉性治疗药物,以向血清素受体的前景.

关键词:
5-HT2A是一种5-HT2A.5-HT2C的使用情况.中毒素是什么意思 中毒素是什么意思在GPCR中,GPCR是指GPCR.头部动反应反应血清激素受体 血清激素受体

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