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Updated: Jul 8, 2026

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随着时间的推移,voxel-wise灰色物质不对称性的变化

Florian Kurth^1,2, Nicolas Cherbuin³, Christian Gaser^4,5,6

¹School of Psychology, University of Auckland, Auckland, New Zealand.

Frontiers in neuroscience

|December 17, 2025

概括

随着年龄的增长,大脑不对称性发生变化,特别是在叶,叶和小脑中. 这些大脑不对称性变化与47-80岁成年人的年代或性别无关.

科学领域:

神经科学是一个神经科学.
人类大脑成像人类大脑成像
衰老研究研究衰老研究

背景情况:

半球大脑不对称性从生命早期就存在,并在整个生命周期内演变.
现有的研究缺乏关于大脑不对称性和受影响区域与年龄相关的变化的方向和规模的共识.

研究的目的:

调查成年人与年龄相关的灰色质异对称的变化.
为了确定大脑不对称性的变化是否根据时间年龄或生物性别而有所不同.

主要方法:

利用了来自2322名参与者 (47至80岁) 的英国生物库数据,并进行了两次MRI扫描.
在平均2.4年的随访期内,分析了克素智的灰色物质不对称性变化.

主要成果:

观察到大脑不对称性的显著变化,主要在叶,叶和小脑中.
总的来说,不对称性下降比增加更常见,具有明显的半球特定模式.
不对称性变化与时间年龄或生物性别之间没有发现显著的关联.

结论:

灰质不对称性在中晚成年期发生显著变化,具有区域特异性.
这些与年龄相关的不对称性变化似乎不会随着年龄的增长而加速或减缓,并且没有性别差异.
需要进一步的研究来探索这些变化跨不同的生命阶段和临床人群.

关键词:

年龄的年龄年龄的年龄.不对称的不对称性大脑大脑大脑的大脑大脑灰色物质是一种灰色物质.在性爱中,性爱是性爱.

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