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瘤性误解变体对人类的Polo样酶1蛋白的功能和结构影响

Gayatri Munieswaran1, Venkatraman Manickam1

  • 1School of Bioscience and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, India.

Frontiers in bioinformatics
|December 17, 2025
PubMed
概括

波罗样酶1 (PLK1) 中的错误突变可以破坏其结构和功能,可能导致癌症. 这项研究确定了高风险的PLK1变体,并将它们的过度表达与多种癌症类型的患者存活率低下联系起来.

关键词:
生物标志物生物标志物癌症 癌症 癌症 癌症 癌症分子动态模拟分子动态模拟在 nsSNP 中使用 nsSNP.在plk1上,你会看到plk1.

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