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Updated: Jan 8, 2026

Novel RNA-Binding Proteins Isolation by the RaPID Methodology
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Novel RNA-Binding Proteins Isolation by the RaPID Methodology

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RAPMS 2.0 提高了RNA结合蛋白的蛋白质识别的特异性和吞吐量

D Honson, W Deng, M Blanco

    bioRxiv : the preprint server for biology
    |December 17, 2025
    PubMed
    概括

    我们开发了RNA反意义净化,其次是质谱2.0 (RAP-MS 2.0) 以改善RNA-蛋白质复合体 (RNP) 的识别. 这种增强的方法减少了背景噪声,并使酸盐可用于多次RNA捕获.

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    相关概念视频

    Ribosome Profiling02:24

    Ribosome Profiling

    Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
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    Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
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