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Updated: Jan 8, 2026

Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography
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B细胞激活因子在CAR-T细胞相关的细胞因子释放综合征中发挥着关键作用

Claire Fritz1, Leland Metheny2, David Wald1,3

  • 1Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA.

bioRxiv : the preprint server for biology
|December 17, 2025
PubMed
概括

在CAR-T治疗中,B细胞激活因子 (BAFF) 驱动细胞因子释放综合征 (CRS). 用贝利马布中和BAFF降低了CRS和ICANS相关的细胞因子,提供了潜在的新治疗策略.

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