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有证据表明酵母Pol ε和PCNA之间的功能相互作用 in vivo

Noopur Singh1, Roni Odai2, Ulf Persson1

  • 1Department of Medical Biochemistry and Biophysics, Umeå University, 901 87 Umeå, Sweden.

Nucleic acids research
|December 17, 2025
PubMed
概括

增殖细胞核抗原 (PCNA) 在复制过程中增强了DNA聚合酶epsilon (Pol ε) 的过程性. 破坏Pol ε-PCNA相互作用会在延长主链合成时减缓生长,揭示PCNA.

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