皮肤内心膜脉冲场切除用于高压阻塞性心肌病:一个病例报告
Yanfeng Tian1, Haoruo Zhang1, Songqing Yang1
1First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.
Pacing and clinical electrophysiology : PACE
|December 17, 2025
概括
皮肤内心隔膜脉冲场切除术 (PES-PFA) 提供了一种治疗高压阻塞性心肌病 (HOCM) 的新方法. 这种创新的程序成功地减少了患者的阻塞,显示了HOCM管理的前景.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 电子生理学 电子生理学
背景情况:
- 超大致阻塞性心肌病 (HOCM) 是心脏病的重要原因.
- 左心室外流管阻塞 (LVOTO) 是HOCM的主要关注点.
- 目前对HOCM的治疗选择有局限性.
研究的目的:
- 评估皮肤内心隔膜脉冲场切除 (PES-PFA) 在HOCM患者的可行性和有效性.
- 评估PES-PFA对左心室外流通道梯度 (LVOTG) 的影响.
主要方法:
- 一名被诊断患有HOCM的53岁男性患者接受了PES-PFA.
- 该程序是指导心内心声谱和3D电解剖绘图系统.
- 通过胸腔心声学 (TTE) 和侵入性血液动力学测量被用于评估.
主要成果:
- 在手术前的LVOTG为73mmHg,而脑脊压梯度为59mmHg.
- 在PES-PFA之后,脑脊压梯度下降到32mmHg.
- 一个月的随访TTE显示LVOTG降低了40mmHg,表明临床改善.
结论:
- PES-PFA代表了一种新且潜在有效的治疗方法,用于HOCM.
- 这一案例证明了PES-PFA在减少LVOTO方面的成功应用.
- 进一步的研究是必要的,以确认PES-PFA在HOCM患者的长期安全性和有效性.
更多相关视频
10:17Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
1.5K
12:45Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
10.9K
相关概念视频
Cardiomyopathy III: Hypertrophic Cardiomyopathy
362
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
362
Cardiomyopathy V: Interprofessional Care
313
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
313
Cardiomyopathy II: Dilated Cardiomyopathy
436
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
436
Cardiomyopathy VII: Pre and Post Operative Nursing Management
257
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
257
