过氧症对儿科输液患者的影响:一个范围审查
Mariah DeRenzo1, Vanessa Velazquez-Milton1, Stepney Johnson1
1Emory University Perfusion Program, Atlanta, GA 30322, USA.
The journal of extra-corporeal technology
|December 17, 2025
概括
儿科心肺绕道术期间的高氧症与严重的并发症有关. 标准化氧气管理和定义高氧症对于儿科心脏手术中的患者安全至关重要.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 关键护理医学 关键护理医学
- 生物医学工程 生物医学工程
背景情况:
- 过氧,或过高的氧气水平,在接受心肺旁路术 (CPB) 的儿科患者中与不良结果有关.
- 这些不良影响包括复氧化损伤,增加死亡率,增加炎症反应和脑损伤.
- 现有的研究显示过氧和负面结果之间存在相关性,但过氧的定义缺乏一致性.
研究的目的:
- 进行范围审查,综合现有的关于儿童CPB患者高氧气的不良影响的文献.
- 根据患者的年龄,色的存在和氧气 (PaO2) 水平的部分压力来分类这些不良影响.
- 确定对标准化氧化管理的需要,以及在这个人群中对高氧化症的一致定义.
主要方法:
- 在主要的数据库中进行了全面的文献搜索:PubMed,CINAHL,Embase和Web of Science.
- 该综述综合了与超氧症及其在儿科CPB患者的不良影响相关的发现.
- 数据根据年龄,蓝色状态和PaO2值进行分类.
主要成果:
- 该审查在研究中确定了高氧化症的不同定义和值.
- 观察到过氧的不良影响,并根据患者人口统计和氧气水平进行分类.
- 在儿科CPB程序中注意到氧气管理协议的显著异质性.
结论:
- 在儿科心肺绕道术中,需要标准化氧化管理协议.
- 一种一致的高氧症定义,区分蓝色和无色色患者,对于准确的研究和临床实践至关重要.
- 实施标准化协议可以减轻副作用,并改善儿科心脏手术患者的治疗结果.
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