在厄瓜多尔家庭中,追踪人类和动物便污染的微生物来源
Kelsey J Jesser1, Viviana Alban1,2, Aldo E Lobos3
1Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.
Applied and environmental microbiology
|December 17, 2025
概括
家庭中的人类和动物便对健康构成风险,特别是对儿童来说. 手和地板是主要的污染点,需要针对人类和动物便来源的干预措施,以减少病原体暴露.
科学领域:
- 环境微生物学环境微生物学
- 公共卫生 公共卫生
- 一个健康,一个健康.
背景情况:
- 家庭中的便污染,特别是在低收入和中等收入国家 (LMICs),对健康构成重大风险,特别是对儿童.
- 对于微生物源追踪 (MST) 标记器实用性在不同家庭环境样本类型中如何变化,人们的理解有限.
研究的目的:
- 确定家庭环境便污染的来源和途径.
- 将护理人员手上的污染与儿童手和地板上的污染联系起来,突出潜在的病原体转移路径.
- 通过在各种样本类型中分析多个宿主相关标记,提供关于便污染生态的见解.
主要方法:
- 对六种MST标记物 (GenBac3,HF183,Rum2Bac,Pig2Bac,DG37,GFD) 进行了验证的qPCR试验.
- 在585个来自59个家庭的样本中,量化标志物的流行率在厄瓜多尔的城市-农村梯度.
- 收集了每户大约10种样本类型,包括洗手液,表面,土壤,水和食物.
主要成果:
- 在77.82%和15.36%的样本中分别检测到一般便污染 (GenBac3) 和与人类相关的标记物 (HF183).
- 与动物相关的标志物较少 (0.5%-4.1%),但存在于与HF183.3相似的度.
- 与宿主相关的标记物在手和地板上最为普遍;GenBac3度在洗手液中最高.
- 成人手上的HF183与儿童手和地板上的检测增加相关.
结论:
- 家庭的手和地板是便污染的重要存储库.
- 干预措施必须解决人类和动物便来源,以有效减少家庭对肠道病原体的暴露.
- 调查结果为采样策略和风险评估提供了信息,以减少儿童在高风险环境中暴露于肠道病原体的风险.
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