全球大脑和中枢神经系统瘤的模式和趋势,按组织学亚型的发病率在185个国家在2022年:一个基于人口的研究研究
Shaoyuan Lei1, Chao Li2, Jiajia Wang3
1Department of Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing Municipal Geriatric Medical Research Center, Beijing, China.
International journal of surgery (London, England)
|December 17, 2025
概括
在2022年,星细胞瘤是最常见的大脑和中枢神经系统 (CNS) 瘤亚型. 了解这些全球发病模式对于制定有针对性的预防和治疗策略至关重要.
科学领域:
- 神经瘤学神经瘤学
- 流行病学 流行病学
- 全球健康 全球健康
背景情况:
- 大脑和中枢神经系统 (CNS) 瘤对全球健康构成重大负担.
- 关于组织学亚型的精确分布的数据有限.
- 准确的流行病学数据对于有效的公共卫生战略至关重要.
研究的目的:
- 量化2022年脑部和中枢神经系统瘤按组织学亚型的全球,区域和国家发病率.
- 分析不同年龄组和人类发展指数 (HDI) 水平之间的发病率变化.
- 评估2003年至2017年大脑和中枢神经系统瘤发病率的时间趋势.
主要方法:
- 利用了来自GLOBOCAN和五大洲癌症发病率 (CI5) X-XII卷的数据.
- 确定了9种不同的脑部和中枢神经系统瘤组织学亚型.
- 计算的年龄标准化发病率 (ASIR),按年龄和人类发育指数分层,使用世界标准人口.
主要成果:
- 在2022年,全球确诊了321,370例新的大脑和中枢神经系统瘤病例 (ASIR:34.6 / 百万).
- 星细胞瘤是最常见的 (173,763例;ASIR:18.5),其次是脑膜和不明来源的质瘤.
- 在全球范围内,按年龄和人体肥胖指数水平观察到亚型比例和ASIR的显著变化.
结论:
- 在2022年,星细胞瘤是最常见的组织学亚型.
- 这些发现提高了对脑瘤流行病学的理解.
- 强调有必要制定量身定制的国家预防和资源分配战略.
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